A clinical study on the efficacy of Lakshadi Gana Taila in Vrana Shodhana w.s.r to its action on microbial load and wound infection

Abstract

Background

Wounds are a significant cause of morbidity worldwide. The science of wound healing is advancing day by day, particularly as a result of new therapeutic advancement. The wound healing effects of different herbal preparations have been described in Sushruta Samhita.

Aim

To evaluate the efficacy of Lakshadi Gana Taila over wound debridement (wound infection and microbial load).

Materials and methods

Lakshadi gana (Laksha , Nimba, Haridra and Amaltas) were collectively prepared to make a taila. This was used to treat patients of infected chronic non healing wounds. The signs and symptoms of infection were graded before and during the course of treatment. Tissue biopsy to estimate the microbial load prior to and during the course of treatment was done.

Results

The clinical symptoms like Pain, Discharge, Tenderness and Malodor in wounds showed statistically reduction following treatment. The microbial load of the wounds was also reduced significantly.

Conclusion

In most of the cases, there was a progressive reduction in the microbial load with time, during the course of treatment indicating the efficacy of the formulation (Lakshadi Gana Taila) in reducing the microbial load and thus controlling infection, facilitating wound healing.