In-Vitro Investigation Of Antioxidant And Antidiabetic Properties Of Plant Extracts
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Abstract
Medicinal plants have consistently served as key sources of medicine around the world. India possesses a vast heritage of traditional medicinal plant resources and is home to diverse plant and animal species. Free radicals are implicated in numerous conditions such as diabetes, inflammation, and cancer, which has increased the interest in antioxidant therapies. Diabetes, a metabolic disorder caused by insufficient insulin or its improper metabolism, has seen a global rise in prevalence, with projections indicating further increases in future generations. Among the various therapeutic approaches to manage diabetes, regulating blood glucose levels through different mechanisms is critical.
This study focus on the In-Vitro investigation of the antioxidant and antidiabetic potential of plant extracts. Phytochemical analysis identified the presence of alkaloids, glycosides, carbohydrates, steroids, and flavonoids in both extracts. Physical properties such as solubility, melting point, ash values, loss on drying (LOD), and extractive values were also examined. The antioxidant activity of the extracts was measured using DPPH and H₂O₂ assays. Additionally, glucose production was assessed through the inhibition of the α-amylase enzyme. Our results demonstrated that Saraca asoca extracts exhibited significant in-vitro antioxidant and antidiabetic activity, indicating that these extracts warrant further investigation in pharmacological studies.
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References
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